Post Tagged with: "cancer"

Salk Researchers Identify Potential Biomarker for Cancer Diagnosis

Salk scientists Martin Hetzer and Emily M. Hatch.Image: Courtesy of the Salk Institute for Biological Studies

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis. In a new study, published [...]

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Genetically Engineered Mouse Models Predict Cancer Drug Responsiveness in Human Tumors

Ultrasound imaging of mouse tumor showing response to chemotherapy. The mouse model allowed researchers to derive a new biomarker of chemotherapy responsiveness.

It’s a GEMM of a system. Genetically engineered mouse models that is. Using them allows scientists to study cancer in a way that more naturally mimics how human tumors exist within the complex environment of the body. UNC scientists used GEMMs to develop biomarkers for challenging molecular subtypes of human [...]

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Researchers Pinpoint Sources of Fibrosis-Promoting Cells That Ravage Organs

Raghu Kalluri, Ph.D., M.D.

Scientists have tracked down and quantified the diverse origins of cells that drive fibrosis, the incurable, runaway wound-healing that scars and ultimately destroys organs such as the lungs, liver and kidneys. Findings from research conducted at Beth Israel Deaconess Medical Center, Harvard Medical School and Massachusetts Institute of Technology in [...]

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West Tennessee Healthcare and Vanderbilt University Medical Center Announce Academic Affiliation Agreement

Artist’s rendering of the Kirkland Cancer Center under construction in Jackson, TN.

Leaders of West Tennessee Healthcare (WTH) and Vanderbilt University Medical Center today announced an academic affiliation agreement which further establishes a collaborative relationship between the two institutions, now for the creation of new cancer programs in West Tennessee.The new agreement creates a framework for the future development of cooperative programs [...]

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Small Molecule Unlocks Key Prostate Cancer Survival Tactic

Small Molecule Unlocks Key Prostate Cancer Survival Tactic

The most recent in a series of studies from a team at the UC Davis Comprehensive Cancer Center has shown that a single molecule is at the heart of one of the most basic survival tactics of prostate cancer cells. A paper published today by the Public Library of Science identifies a [...]

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Novel Inhibitor to Overcome Drug Resistance Induced by RAF, MEK Inhibitors

Novel Inhibitor to Overcome Drug Resistance Induced by RAF, MEK Inhibitors

A new class of investigational medicines may help to treat patients with cancers driven by mutations in genes such as BRAF or KRAS/NRAS, including those patients who have become resistant to therapies that target BRAF directly, according to preclinical data presented at the AACR Annual Meeting 2013, held in Washington, [...]

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Two-Step Ovarian Cancer Immunotherapy Made from Patients’ Own Tumor Benefits Three Quarters of Trial Patients

Two-Step Ovarian Cancer Immunotherapy Made from Patients’ Own Tumor Benefits Three Quarters of Trial Patients

As many as three quarters of advanced ovarian cancer patients appeared to respond to a new two-step immunotherapy approach — including one patient who achieved complete remission — according research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today in a press conference [...]

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